On South Main Street in Canandaigua, the Ontario County Chamber of Commerce brings together over 500 member organizations, fostering connections between businesses, travelers, and investors in the Finger Lakes region. As a non-profit business association, the Chamber cultivates its members' talents and inter-agency alliances to drive personal, professional, and economic prosperity. The organization provides resources and opportunities for members to learn, grow, and share, including professional development and legislative programming. Its center-city facilities serve as a hub for community activities and events.

The Chamber's work is guided by its values of belonging, collaboration, commitment, excellence, quality, and respect, making it a valuable resource for businesses of all sizes in Ontario and contiguous counties. With a range of programs, events, and opportunities, the Chamber supports small, mid-sized, and large businesses, as well as individuals, in achieving their goals and contributing to the region's quality of life, vitality of business, and richness of culture. By partnering with local organizations and marshaling resources, the Chamber amplifies the impact of individuals' efforts, retaining the small-town sensibility that defines Canandaigua.